The Essence of Bipolar Disorder

“Dr. Walsh takes us on a journey through the latest in genetic and neurological research, guiding us to the cause, an explanation for mania-depression transitions, and treatment opportunities. A must-read for scientists, researchers, and physicians seeking answers for bipolar disorder.”—Eva Edelman, author of Natural Healing for Bipolar Disorder“Dr. Walsh is a visionary voice shaping modern psychiatry. He writes from the front lines of biochemical research, where his groundbreaking work has already lifted thousands out of the shadows of depression, anxiety, ADHD, and other struggles.”—Sarah Warley, founder of the Key Clinic, London“Dr. William Walsh, a pioneer in Mastering Brain Chemistry, turns his sharp focus to the intricate biology of bipolar disorder. This work uniquely integrates diverse scientific breakthroughs—exploring everything from molecular genetics and ion channel dysfunction to neuronal injury and glia.”—Ronald Glick, psychiatrist, University of Pittsburgh School of Medicine“Dr. Walsh’s work offers a clinically relevant framework for understanding bipolar disorder through the lens of neuroscience, genetics, and epigenetics. His insights into the biological basis of mood switching may guide more targeted interventions and future strategies for prevention.”—Dr. Inna Merenzon, forensic psychiatrist, Israel“The groundbreaking discoveries and brilliance of Dr. William J. Walsh will educate you about the realities of this previously elusive and very mysterious disorder. Dr. Walsh has studied over 30,000 mental patients, acquired a database of over 3 million chemical assays, and trained more than 1,000 doctors in novel protocols which correct imbalances in brain chemistry.”—Teri Arranga, president emeritus, Autism International Association“Dr. Walsh has cracked the code on bipolar disorder in ways that will fundamentally transform treatment. He reveals the genetic vulnerabilities and accelerated oxidative assaults that actually cause the condition. This revolutionary understanding offers real hope beyond traditional approaches.”—Aimie Apigian, MD, developer of The Biology of Trauma®“Dr. Walsh’s groundbreaking research draws on recent advances in neuroscience, genetics, epigenetics, and DNA repair to reveal bipolar disorder’s biological roots. His explanation of mood switching brings long-overdue clarity and hope. As a medical professional following his work with genuine admiration, I strongly believe it holds life-changing promise for patients and families.”—Antoinette Föhr-Keller, MD, Switzerland“Dr. Walsh’s ideas about the fundamental underpinnings of mental health laid a new foundation to my approach for mental health treatment and a dramatic benefit in my patients’ lives, helping patients feel better, reduce medications, and sometimes resolve problems that conventional medical treatment never helped. His ability to parse out root causes of psychiatric illness continues to improve people’s lives around the world.” —Malcolm Sickels, MD, Ann Arbor, Michigan“This book takes you on a fascinating in-depth journey into the functional biochemistry of neurons, DNA, and the supporting network of glia cells in a methodical way, making the complex understandable. Dr. Walsh comes to an illuminating conclusion about the cause of bipolar disorder and proposes preventive strategies and a framework for future research and treatments.”—Kenneth Cartaxo, MD

Dr. William J. Walsh

Protecting DNA.