A Biomolecular And Conformational Investigation Of Protein Ub Conjugation Processes Driven By RING-Domain Ub Transfer Enzymes

Unlocking the Secrets of Ubiquitin: A Deep Dive into Protein Conjugation

Cells are masters of adaptation, constantly responding to their surroundings to survive and thrive. This intricate dance is orchestrated by signaling networks that detect stimuli and trigger changes in cellular behavior, from tweaking gene expression to activating or suppressing protein functions.

A key element of this process is post-translational modifications (PTMs), where molecules are attached to p…