Mineralizing Vesicles

”…focuses on the often-overlooked process of biomineralization, which depends on extracellular vesicles to serve as vehicles for conveying inorganic materials to the sites of biomineralization in the body…. [T]he first comprehensive and up-to-date resource covering all aspects of mineralizing extracellular vesicles, from composition and function to pathophysiology and clinical potential…. [A]kin to an encyclopedic resource,… written in a clear, direct, and economical manner that students will find preferable to the parade of long, grammatically complex sentences that often dominate technical writing. The book is concise and contents well-organized,… contains a generous list of references, which contain a weblinks for easy access. [A] well-written book that is particularly well-suited for college, graduate, and professional students. Given the biomedical significance of its subject matter, comprehensive coverage, and clarity of presentation, it represents a particularly valuable resource for a biomedical library.” –©Doody’s Review Service, 2024, Peter J. Kennelly, PhD (Virginia Tech)

Massimo Bottini is Associate Professor of Biochemistry at the University of Rome Tor Vergata (Rome, Italy) since 2015. As previous positions, he has been Affiliate Associate Professor at the Sanford Burnham Prebys (La Jolla, USA) from 2015 to 2022, and Visiting Professor at the University of the Chinese Academy of Sciences (Beijing, People’s Republic of China) from 2017 to 2019 and at the University of São Paulo (São Paulo, Brazil) in 2020. He has been the recipient of fellowships/grants from the Juvenile Diabetes Research Foundation, the Arthritis National Research Foundation, the European Commission, the University of Rome Tor Vergata, and the Chinese Academy of Sciences. He leads the Laboratory of Biochemical Nanotechnology at the University of Rome Tor Vergata. His research is mostly focused on the characterization of the biochemical and biophysical properties of the extracellular vesicles released during physiologic and ectopic biomineralization processes.

Ana Paula Ramos is an Associate Professor at the University of Paulo-Brazil. She got her first degree in Chemistry in 2004 and a Ph.D. in Physical Chemistry in 2009. She is currently an associate Professor of Physical Chemistry, at the University of São Paulo Brazil and a researcher of the Brazilian National Council for Scientific and Technological Development (CNPq). She is the coordinator of the Physical Chemistry of Colloids and Surfaces Laboratory, with expertise in surfaces modification and characterization by microscopic and spectroscopic techniques. Her main research interests are the synthesis of biomaterials for bone replacement and regeneration. In special, her current projects focus on the use of biomimetic matrices inspired by the interaction of phospholipids and osteogenic proteins found in matrix vesicles as modifiers of metals used for dental implants. Moreover, she is currently investigating the role of strontium on physiological and pathological mineralization.

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