Molecular Biology of Cancer

Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers an accessible, engaging, and optimistic account of cancer biology for undergraduate and graduate students. Using the hallmarks of cancer as a starting point, the book looks at the cellular and molecular mechanisms underpinning the transformation of cells into cancer cells. After discussing the theory, each chapter then demonstrates how this knowledge can bedirectly applied to the development of new targeted therapies, giving the reader a clear appreciation of how our understanding of the theory can be translated into new approaches for tackling thedisease. The new edition draws on the latest research in cancer biology, highlighting fundamental concepts and re-emphasising pre-existing concepts. The book features a variety of learning features - 'Pause and think', 'How do we know that?', self-tests and activities - to help students engage with, and master, the concepts presented. The emphasis is on acquiring a solid understanding of the essentials and an appreciation of how a theoretical understanding can betransformed into therapeutic benefit. Molecular Biology of Cancer is supported by online resources and is available for students and institutions to purchase in a variety of formats.The e-book offers a mobile experience and convenient access along with functionality tools, navigation features and links that offer extra learning support: The online resources include: For students: - Multiple choice questions - Web links to additional cancer biology resources For registered adopters of thebook: · Figures from the book, available to download

“I think this is a very well written book, the features are clear and concise and it's very easy and pleasing to follow and understand. It's covered a wide range of topics and the figures/diagrams are excellent. The features such as pause and think and pioneers in the field are such a great touch.”

Blyth Richards, Student, Swansea University
This textbook has extensive learning features that help to improve the reader's user experience and knowledge of scientific concepts. It is extremely well detailed and concise with a clear structure throughout. Specialised when needed, simplified whenever possible, highly recommend. Daniel O'Neill, Student, Aberystwyth University
This textbook is a clear and comprehensive overview of molecular biology in the context of cancer research and treatment. It is accessible to undergraduates and a helpful refresher for postgraduates as well. Holly English, Student, University College Dublin
I loved this book! It is stimulating and makes some very challenging work readable and accessible. The various learning features are useful and supportive, and serve to encourage a [strong] level of engagement. Gary Edward Spencer, Student, Canterbury Christ Church University
Overall I feel that the way in which the book explains complex mechanisms is outstanding. Where other textbooks can often leave you feeling perplexed, this textbook simplifies everything into manageable chunks. Rebecca Kemp, Student, University of Nottingham
This book provides a comprehensive grounding for students who want to investigate cancer mechanisms. It contains helpful active learning activities to ensure that students can understand, and most importantly, apply their knowledge to real life scenarios. Dr Sarah Bailey, University of Surrey
A good overview of the current understanding of the molecular events in cancer biology and how they are being exploited for targeting cancer treatments at the molecular level. Dr Christopher Mee, University of Leicester

Dr Lauren Pecorino obtained her PhD in Cell and Developmental Biology at the State University of New York at Stony Brook, USA. She then moved to London to carry out a post-doctoral tenure at the Ludwig Institute for Cancer Research where she studied the phenomenon of limb regeneration. Here she used a technique called biolistics, using a 'gene gun' to shoot gold bullets coated with DNA to introduce genes into the regenerating limbs of live newts. Since 1996, Laurenhas been a member of academic staff at the University of Greenwich, where she developed her interest in teaching Cancer Biology. In 2018, Lauren was made a Principal Fellow of the Higher EducationAcademy.

Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers an accessible, engaging, and optimistic account of cancer biology for undergraduate and graduate students. Using the hallmarks of cancer as a starting point, the book looks at the cellular and molecular mechanisms underpinning the transformation of cells into cancer cells. After discussing the theory, each chapter then demonstrates how this knowledge can be directly applied to the development of new targeted therapies, giving the reader a clear appreciation of how our understanding of the theory can be translated into new approaches for tackling the disease.The new edition draws on the latest research in cancer biology, highlighting fundamental concepts and re-emphasising pre-existing concepts. The book features a variety of learning features - 'Pause and think', 'How do we know that?', self-tests and activities - to help students engage with, and master, the concepts presented. The emphasis is on acquiring a solid understanding of the essentials and an appreciation of how a theoretical understanding can be transformed into therapeutic benefit. Molecular Biology of Cancer is supported by online resources and is available for students and institutions to purchase in a variety of formats. The e-book offers a mobile experience and convenient access along with functionality tools, navigation features and links that offer extra learning support: The online resources include:For students:- Multiple choice questions- Web links to additional cancer biology resourcesFor registered adopters of the book:

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