Vascular Cognitive Impairment in Clinical Practice

Vascular cognitive impairment is the second most common cause of dementia after Alzheimer's disease and is expected to grow in prevalence with the aging global population. The purpose of this authoritative book is to give a broad clinical perspective on vascular cognitive impairment and thus create a foundation for the implementation of good dementia care. The book focuses on pathophysiology, diagnosis, treatment and prevention. It demonstrates the underlying causes of the disorder, such as the manner in which vascular risk-factors influence the onset of vascular cognitive impairment. The concept of mixed forms of vascular dementia, Alzheimer's dementia and other vascular diseases is discussed as well as the influence of vascular changes with regard to the onset of Alzheimer's disease. The detailed section on pathophysiology will enhance clinicians' understanding of this complex disorder. Finally there is a section on pharmacological and neuropsychological treatment of cognitive and psychiatric symptoms.

“"This multiauthored monograph chronicles how changes in brain blood vessels affect cognition and cause dementia and other related syndromes. It is a brilliant synthesis of a complicated topic, drawing together knowledge and recent discoveries from a wide variety of disciplines....This is a major contribution to the field. It sorts out in clear fashion a very tangled literature. In the process, it points out just where future research is needed. Methodological issues of such research and the profound implications of epidemiological studies (vascular disease starts early and causes cognitive changes in midlife) are emphasized. In addition, the book provides clear outlines of the approach to differential diagnosis and management of these patients, including caregiver support. Finally, the links of heart disease to both vascular cognitive impairment and Alzheimer's disease are discussed. The excellent organization and editing of this book, its careful elaboration of complex concepts, and the practical application of this synthesis give rise to a first-rate work. This much-needed book deserves a wide readership." --Doody's Review Service”

'… this book may be recommended not just for the VaD/VCI cognoscenti, but for all those concerned with the diagnosis and management of dementia syndromes.' Advances in Clinical Neuroscience and Rehabilitation
'This is a major contribution to the field. It sorts out in clear fashion a very tangled literature. … The excellent organisation and editing of this book, its careful elaboration of complex concepts, and the practical application of this synthesis give rise to a first-rate work. This much-needed book deserves a wide readership.' David O. Staats MD, University of Oklahoma Health Sciences Center

Lars-Olof Wahund is a Professor at the Department of Neurobiology, Caring Sciences and Society at the Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm, Sweden. Timo Erkinjuntti is Professor of Neurology at the Department of Neurology, University of Helsinki, Helsinki, Finland. Serge Gauthier is a Professor and Director at the Alzheimer's Disease and Related Disorders Research Unit, McGill Centre for Studies on Aging, Douglas Mental Health University Institute, Montréal, Québec, Canada.

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