RNA as a Drug Target
The Next Frontier for Medicinal Chemistry
$380.09
- Hardcover
416 pages
- Release Date
7 August 2024
Summary
Discover a new paradigm in drug discovery that greatly expands the space of addressable drug targets and potential novel drugs
Existing paradigms for drug discovery have focused largely on enzymes and other proteins as drug targets. In recent years, however, different varieties of ribonucleic acids have emerged as a viable focus for target-based drug discovery, with the potential to revolutionize the strategy and approach for this essential step in the drug developmen…
Book Details
| ISBN-13: | 9783527351008 |
|---|---|
| ISBN-10: | 3527351000 |
| Author: | John Schneekloth, Martin Pettersson, Raimund Mannhold, Helmut Buschmann, Jörg Holenz |
| Publisher: | Wiley-VCH Verlag GmbH |
| Imprint: | Blackwell Verlag GmbH |
| Format: | Hardcover |
| Number of Pages: | 416 |
| Release Date: | 7 August 2024 |
| Weight: | 680g |
| Dimensions: | 15mm x 170mm x 244mm |
| Series: | Methods & Principles in Medicinal Chemistry |
John Schneekloth
John Schneekloth, Jr., PhD (Jay), obtained his PhD from the chemistry department of Yale University. Following postdoctoral work at Princeton, Dr. Schneekloth joined the NCI, where his research involves using synthetic chemistry and high throughput chemical biology approaches to develop chemical probes of RNA, with a particular emphasis on targeting RNA with druglike small molecules.
Martin Pettersson, PhD, obtained his PhD in Organic Chemistry from the University of Texas at Austin. He is a medical chemistry / drug discovery leader with over 20 years of industrial experience, mainly with Pfizer (co-inventor of Paxlovid). He has then continued as Senior Director of Neuroscience/Pain, Chemistry, at Grünenthal Boston Innovation Hub, and most recently as VP of Drug Discovery at Promedigen in South Korea.
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