
Regulating with RNA in Bacteria and Archaea
$373.97
- Hardcover
575 pages
- Release Date
31 October 2018
Summary
Revealing the many roles of RNA in regulating gene expression
For decades after the discoveries of messenger RNA, transfer RNA, and ribosomal RNA, it was largely assumed that the role of RNA in the cell was limited to shuttling the genomic message, chaperoning amino acids, and toiling in the ribosomes.
Eventually, hints that RNA molecules might have regulatory roles began to appear. With the advent of genomics and bioinformatics, it became evident that numerous other RNA form…
Book Details
| ISBN-13: | 9781683670230 |
|---|---|
| ISBN-10: | 168367023X |
| Author: | Gisela Storz, Kai Papenfort |
| Publisher: | American Society for Microbiology |
| Imprint: | American Society for Microbiology |
| Format: | Hardcover |
| Number of Pages: | 575 |
| Release Date: | 31 October 2018 |
| Weight: | 1.97kg |
| Dimensions: | 282mm x 218mm x 36mm |
| Series: | ASM Books |
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What They're Saying
Critics Review
Finally! One spectacular volume provides us all we need to educate ourselves in the fascinating world of regulatory RNAs in bacteria and archaea. From the genetics to the biochemistry to the mechanisms to the structures to the physiology to the networks to the challenges for the future—it’s all here—laid out for us in exceptional form by the world’s key experts. This volume is an eye-opening must read about one of microbiology’s most exciting emerging fields.
-Bonnie L. Bassler, Ph.D., HHMI Investigator, Squibb Professor and Chair of the Department of Molecular Biology, Princeton University
About The Author
Gisela Storz
Gisela Storz is an NIH Distinguished Investigator in the Eunice Kennedy Shriver National Institute of Child Health and Human Development in Bethesda, Maryland. She carried out graduate work with Dr. Bruce Ames at the University of California, Berkeley and postdoctoral work with Dr. Sankar Adhya at the National Cancer Institute and Dr. Fred Ausubel at Harvard Medical School. As a result of the serendipitous discovery of the peroxide-induced OxyS RNA in E. coli, one of the first small, regulatory RNAs to be found, much of the work in her lab has focused on the genome-wide identification of small RNAs and their characterization.
Kai Papenfort is a Professor of Microbiology at the Ludwig Maximilians University of Munich, Germany. He received a diploma in biology from the University of Marburg and carried out graduate work with Dr. Jörg Vogel at the Max Planck Institute for Infection Biology and the Humboldt University of Berlin. In his postdoctoral work at the University of Würzburg and Princeton University, Dr. Papenfort studied the regulatory functions of small RNA in bacterial pathogens and their involvement in bacterial communication processes such as quorum sensing. His laboratory focuses on the molecular mechanisms underlying the regulation by small RNAs in the major human pathogen, Vibrio cholerae.
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