Telomerases, 1st Edition
Chemistry, Biology, and Clinical Applications
$364.15
- Hardcover
318 pages
- Release Date
11 June 2012
Summary
This book is a comprehensive and up-to-date review and evaluation of the contemporary status of telomerase research. Chapters in this volume cover the basic structure, mechanisms, and diversity of the essential and regulatory subunits of telomerase. Other topics include telomerase biogenesis, transcriptional and post-translational regulation, off-telomere functions of telomerase and the role of telomerase in cellular senescence, aging and cancer. Its relationship to retrotransposons, a class …
Book Details
| ISBN-13: | 9780470592045 |
|---|---|
| ISBN-10: | 0470592044 |
| Author: | Chantal Autexier, Neal F. Lue |
| Publisher: | John Wiley & Sons Inc |
| Imprint: | John Wiley & Sons Inc |
| Format: | Hardcover |
| Number of Pages: | 318 |
| Edition: | 1st |
| Release Date: | 11 June 2012 |
| Weight: | 611g |
| Dimensions: | 241mm x 163mm x 23mm |
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About The Author
Chantal Autexier
NEAL F. LUE, MD, PHD, is Professor in the Department of Microbiology and Immunology at Weill Cornell Medical College. He received his BS from Johns Hopkins University and his MD and PhD from Stanford University. His laboratory studies the structures and mechanisms of the telomere and telomerase complexes in a variety of fungal model systems.
CHANTAL AUTEXIER, PHD, is Professor in the Department of Anatomy and Cell Biology and the Department of Medicine at McGill University. She received her BSc from Concordia University and her PhD from McGill University. Her laboratory studies the mechanisms that regulate telomerase and telomere functions in mammalian cells, and evaluates the principles of anticancer strategies that target these mechanisms.
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